Design, Characterization, and Applications of Molecular Force Sensor

This dissertation contains info about array, atomic force microscope, surface, single molecule, protein arrays, interactions, activity, atomic force, contact process, and force extension. Lots of explanation around rupture force, fusion, antigen interactions, bond, sensor, reaction, molecule force spectroscopy, molecular force, slipping force, and double chip format are explained inside the dissertation.

Inside the dissertation you can get info such as molecule, sequence, immobilization, molecular force sensors, experiments, force, force spectroscopy, surface plasmon resonance, detection, and differential force. These are chosen from this dissertation:

Howev er, measuring c hanges in enzy matic activity requires more sophisticated experimental approaches, such as t he ones described in this work. Onc e the res ponse of a biomolec ule to an external force has been characterized, this knowledge provides the blue print for the design of artificial forc e sensors, which act in a similar way as naturally occurring forc e sensors. As soon as a cert ain threshold forc e is reac hed, the artificial forc e sensors s how a desired and defined respons e. Wit hin t he scope of this work t wo different artif icial forc e sensors hav e been designed, characterized and applied to analyze biological systems

Even more, this dissertation presents information things like capture arrays, fluorescence, capture array, chip surface, force sensor, externally applied force, recombinant antibody, system, fluorescence intensities, and active site.

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